Zebrafish Adar2 Edits the Q/R Site of AMPA Receptor Subunit gria2α Transcript to Ensure Normal Development of Nervous System and Cranial Neural Crest Cells

BACKGROUND: Adar2 deaminates selective adenosines to inosines (A-to-I RNA editing) in the double-stranded region of nuclear transcripts. Although the functions of mouse Adar2 and its biologically most important substrate gria2, encoding the GluA2 subunit of AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazo...

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Detalles Bibliográficos
Autores principales: Li, I-Chen, Chen, Yu-Chia, Wang, Yi-Yun, Tzeng, Bo-Wei, Ou, Chun-Wen, Lau, Yi-Yan, Wu, Kan-Mai, Chan, Tzu-Min, Lin, Wei-Hsiang, Hwang, Sheng-Ping L., Chow, Wei-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018279/
https://www.ncbi.nlm.nih.gov/pubmed/24818983
http://dx.doi.org/10.1371/journal.pone.0097133

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