Cargando…

Melatonin Inhibits Endoplasmic Reticulum Stress and Epithelial-Mesenchymal Transition during Bleomycin-Induced Pulmonary Fibrosis in Mice

Several reports indicate that melatonin alleviates bleomycin (BLM)-induced pulmonary fibrosis in rodent animals. Nevertheless, the exact mechanism remains obscure. The present study investigated the effects of melatonin on endoplasmic reticulum (ER) stress and epithelial-mesenchymal transition (EMT)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Hui, Wu, Qing-Qing, Cao, Lin-Feng, Qing, Hou-Ying, Zhang, Cheng, Chen, Yuan-Hua, Wang, Hua, Liu, Rong-Ru, Xu, De-Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018327/ https://www.ncbi.nlm.nih.gov/pubmed/24818755 http://dx.doi.org/10.1371/journal.pone.0097266

Ejemplares similares

Isorhamnetin protects against bleomycin-induced pulmonary fibrosis by inhibiting endoplasmic reticulum stress and epithelial-mesenchymal transition
por: Zheng, Qing, et al.
Publicado: (2019)

Correction: Melatonin Inhibits Endoplasmic Reticulum Stress and Epithelial-Mesenchymal Transition during Bleomycin-Induced Pulmonary Fibrosis in Mice
Publicado: (2015)

Tauroursodeoxycholic acid alleviates pulmonary endoplasmic reticulum stress and epithelial-mesenchymal transition in bleomycin-induced lung fibrosis
por: Tong, Bin, et al.
Publicado: (2021)

Bleomycin induces epithelial-to-mesenchymal transition via bFGF/PI3K/ESRP1 signaling in pulmonary fibrosis
por: Weng, Chang-Mei, et al.
Publicado: (2020)

Hypoxia-Induced Epithelial-Mesenchymal Transition Is Involved in Bleomycin-Induced Lung Fibrosis
por: Guo, Liang, et al.
Publicado: (2015)

Vincamine Ameliorates Epithelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis in Rats; Targeting TGF-β/MAPK/Snai1 Pathway
por: Alaaeldin, Rania, et al.
Publicado: (2023)

Endoplasmic reticulum stress promotes epithelial-mesenchymal transition via the PERK signaling pathway in paraquat-induced pulmonary fibrosis
por: Meng, Xiaoxiao, et al.
Publicado: (2021)

2-aminopurine suppresses the TGF-β1-induced epithelial–mesenchymal transition and attenuates bleomycin-induced pulmonary fibrosis
por: Weng, Dong, et al.
Publicado: (2018)

Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation
por: Guan, Ruijuan, et al.
Publicado: (2016)

Calpain inhibition attenuates bleomycin-induced pulmonary fibrosis via switching the development of epithelial-mesenchymal transition
por: Liu, Yuan, et al.
Publicado: (2018)

Atractylodin Suppresses TGF-β-Mediated Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells and Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Chang, Kai-Wei, et al.
Publicado: (2021)

Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-β/Smad2/3-mediated epithelial-mesenchymal transition
por: Li, Se-Ruo, et al.
Publicado: (2019)

Bleomycin-enhanced alternative splicing of fibroblast growth factor receptor 2 induces epithelial to mesenchymal transition in lung fibrosis
por: Chen, Kui-Jun, et al.
Publicado: (2018)

Endoplasmic reticulum stress regulates epithelial-mesenchymal transition in human lens epithelial cells
por: Zhou, Sheng, et al.
Publicado: (2020)

Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial–mesenchymal transition and fibroblast activation
por: Chen, Y-L, et al.
Publicado: (2013)

Astragaloside IV modulates TGF‐β1‐dependent epithelial‐mesenchymal transition in bleomycin‐induced pulmonary fibrosis
por: Qian, Weibin, et al.
Publicado: (2018)

NecroX-5 ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3-mediated epithelial–mesenchymal transition
por: Min, Li, et al.
Publicado: (2022)

GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition
por: Zhou, Xiao-Ming, et al.
Publicado: (2017)

Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway
por: Li, Jiang, et al.
Publicado: (2023)

Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats
por: Wan, Yun-Yan, et al.
Publicado: (2013)

Epithelial-Mesenchymal Transition Induces Endoplasmic-Reticulum-Stress Response in Human Colorectal Tumor Cells
por: Zeindl-Eberhart, Evelyn, et al.
Publicado: (2014)

The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition
por: Feng, Yu-xiong, et al.
Publicado: (2014)

Hydrogen Sulfide Inhibits Bronchial Epithelial Cell Epithelial Mesenchymal Transition Through Regulating Endoplasm Reticulum Stress
por: Lin, Fan, et al.
Publicado: (2022)

Histone deacetylase 3 deletion in alveolar type 2 epithelial cells prevents bleomycin-induced pulmonary fibrosis
por: Xiong, Rui, et al.
Publicado: (2023)

Megakaryocytes participate in the occurrence of bleomycin-induced pulmonary fibrosis
por: Zhou, Yan, et al.
Publicado: (2019)

Expression of pulmonary aquaporin 1 is dramatically upregulated in mice with pulmonary fibrosis induced by bleomycin
por: Gao, Xiwen, et al.
Publicado: (2012)

PRDX1 negatively regulates bleomycin-induced pulmonary fibrosis via inhibiting the epithelial-mesenchymal transition and lung fibroblast proliferation in vitro and in vivo
por: Sun, Hu-Nan, et al.
Publicado: (2023)

IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells
por: Gong, Ling, et al.
Publicado: (2020)

Effect of alendronate sodium on the expression of mesenchymal-epithelial transition markers in mice with liver fibrosis
por: BI, WAN-RONG, et al.
Publicado: (2013)

Epithelial–Mesenchymal Transition in the Pathogenesis of Idiopathic Pulmonary Fibrosis
por: Salton, Francesco, et al.
Publicado: (2019)

Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice
por: Liu, Wei, et al.
Publicado: (2013)

Endothelial-specific Loss of IFT88 Promotes Endothelial-to-Mesenchymal Transition and Exacerbates Bleomycin-induced Pulmonary Fibrosis
por: Singh, Shweta, et al.
Publicado: (2020)

Nintedanib reduces ventilation‐augmented bleomycin‐induced epithelial–mesenchymal transition and lung fibrosis through suppression of the Src pathway
por: Li, Li‐Fu, et al.
Publicado: (2017)

Yangyin Yiqi Mixture Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats through Inhibiting TGF-β1/Smad Pathway and Epithelial to Mesenchymal Transition
por: Meng, Lihong, et al.
Publicado: (2019)

Mesenchymal Stem Cells Inhibit Epithelial-to-Mesenchymal Transition by Modulating the IRE1α Branch of the Endoplasmic Reticulum Stress Response
por: Luo, Ruixi, et al.
Publicado: (2023)

Endoplasmic Reticulum Stress Induces CAP2 Expression Promoting Epithelial-Mesenchymal Transition in Liver Cancer Cells
por: Yoon, Sarah, et al.
Publicado: (2021)

Bleomycin (BLM) Induces Epithelial-to-Mesenchymal Transition in Cultured A549 Cells via the TGF-β/Smad Signaling Pathway
por: Chen, Kui-Jun, et al.
Publicado: (2016)

Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition
por: Kyung, Sun Young, et al.
Publicado: (2018)

Role of Ferroptosis in Regulating the Epithelial–Mesenchymal Transition in Pulmonary Fibrosis
por: Ling, Hong, et al.
Publicado: (2023)

Hypoxia-preconditioned mesenchymal stem cells attenuate bleomycin-induced pulmonary fibrosis
por: Lan, Ying-Wei, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dravlph3lh172nq43qv6d30fso