Predicting mTOR Inhibitors with a Classifier Using Recursive Partitioning and Naïve Bayesian Approaches

BACKGROUND: Mammalian target of rapamycin (mTOR) is a central controller of cell growth, proliferation, metabolism, and angiogenesis. Thus, there is a great deal of interest in developing clinical drugs based on mTOR. In this paper, in silico models based on multi-scaffolds were developed to predict...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Chen, Lei, Liu, Zhihong, Zheng, Minghao, Gu, Qiong, Xu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018356/
https://www.ncbi.nlm.nih.gov/pubmed/24819222
http://dx.doi.org/10.1371/journal.pone.0095221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018356/
https://www.ncbi.nlm.nih.gov/pubmed/24819222
http://dx.doi.org/10.1371/journal.pone.0095221

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