Treatment with the NK1 Antagonist Emend Reduces Blood Brain Barrier Dysfunction and Edema Formation in an Experimental Model of Brain Tumors

The neuropeptide substance P (SP) has been implicated in the disruption of the blood-brain barrier (BBB) and development of cerebral edema in acute brain injury. Cerebral edema accumulates rapidly around brain tumors and has been linked to several tumor-associated deficits. Currently, the standard t...

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Detalles Bibliográficos
Autores principales: Harford-Wright, Elizabeth, Lewis, Kate M., Ghabriel, Mounir N., Vink, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018359/
https://www.ncbi.nlm.nih.gov/pubmed/24818961
http://dx.doi.org/10.1371/journal.pone.0097002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018359/
https://www.ncbi.nlm.nih.gov/pubmed/24818961
http://dx.doi.org/10.1371/journal.pone.0097002

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