Human Osteoarthritic Cartilage Shows Reduced In Vivo Expression of IL-4, a Chondroprotective Cytokine that Differentially Modulates IL-1β-Stimulated Production of Chemokines and Matrix-Degrading Enzymes In Vitro

BACKGROUND: In osteoarthritis (OA), an inflammatory environment is responsible for the imbalance between the anabolic and catabolic activity of chondrocytes and, thus, for articular cartilage derangement. This study was aimed at providing further insight into the impairment of the anabolic cytokine...

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Detalles Bibliográficos
Autores principales: Assirelli, Elisa, Pulsatelli, Lia, Dolzani, Paolo, Platano, Daniela, Olivotto, Eleonora, Filardo, Giuseppe, Trisolino, Giovanni, Facchini, Andrea, Borzì, Rosa Maria, Meliconi, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018406/
https://www.ncbi.nlm.nih.gov/pubmed/24819779
http://dx.doi.org/10.1371/journal.pone.0096925

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