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Expression of endogenous Mkp1 in 6-OHDA rat models of Parkinson’s disease

We have previously demonstrated that mitogen-activated protein kinase phosphatase 1, Mkp1, is expressed in the developing and rat adult substantia nigra and striatum, where it promotes the growth of nigral dopaminergic neurons. Mkp1 may therefore have therapeutic potential for Parkinson’s disease. I...

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Detalles Bibliográficos
Autores principales: Collins, Louise M, Gavin, Aisling M, Walsh, Sinead, Sullivan, Aideen M, Wyatt, Sean L, O’Keeffe, Gerard W, Nolan, Yvonne M, Toulouse, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018472/
https://www.ncbi.nlm.nih.gov/pubmed/24826373
http://dx.doi.org/10.1186/2193-1801-3-205