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Oxidative stress promotes d-GalN/LPS-induced acute hepatotoxicity by increasing glycogen synthase kinase 3β activity

OBJECTIVE: Our previous studies have demonstrated that glycogen synthase kinase 3β (GSK3β) activity is increased in the progression of acute liver failure (ALF), which aggravates liver injury, while its regulatory mechanism remains elusive. This study is designated to address whether oxidative stres...

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Detalles Bibliográficos
Autores principales: Wei, Linlin, Ren, Feng, Zhang, Xiangying, Wen, Tao, Shi, Hongbo, Zheng, Sujun, Zhang, Jing, Chen, Yu, Han, Yuanping, Duan, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018480/
https://www.ncbi.nlm.nih.gov/pubmed/24531650
http://dx.doi.org/10.1007/s00011-014-0720-x