Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex

The subunits of the nonspecific lethal (NSL) complex, which include the histone acetyltransferase MOF (males absent on the first), play important roles in various cellular functions, including transcription regulation and stem cell identity maintenance and reprogramming, and are frequently misregula...

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Detalles Bibliográficos
Autores principales: Dias, Jorge, Van Nguyen, Nhuong, Georgiev, Plamen, Gaub, Aline, Brettschneider, Janine, Cusack, Stephen, Kadlec, Jan, Akhtar, Asifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018492/
https://www.ncbi.nlm.nih.gov/pubmed/24788516
http://dx.doi.org/10.1101/gad.240200.114

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