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Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts
The transcription factor SRF (serum response factor) recruits two families of coactivators, the MRTFs (myocardin-related transcription factors) and the TCFs (ternary complex factors), to couple gene transcription to growth factor signaling. Here we investigated the role of the SRF network in the imm...
Autores principales: | Esnault, Cyril, Stewart, Aengus, Gualdrini, Francesco, East, Phil, Horswell, Stuart, Matthews, Nik, Treisman, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018493/ https://www.ncbi.nlm.nih.gov/pubmed/24732378 http://dx.doi.org/10.1101/gad.239327.114 |
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