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Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration

Accidental or deliberate ionizing radiation exposure can be fatal due to widespread hematopoietic destruction. However, little is known about either the course of injury or the molecular pathways that regulate the subsequent regenerative response. Here we show that the Wnt signaling pathway is criti...

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Detalles Bibliográficos
Autores principales: Lento, William, Ito, Takahiro, Zhao, Chen, Harris, Jeffrey R., Huang, Wei, Jiang, Chen, Owzar, Kouros, Piryani, Sadhna, Racioppi, Luigi, Chao, Nelson, Reya, Tannishtha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018497/
https://www.ncbi.nlm.nih.gov/pubmed/24788518
http://dx.doi.org/10.1101/gad.231944.113