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The p53-induced factor Ei24 inhibits nuclear import through an importin β–binding–like domain
The etoposide-induced protein Ei24 was initially identified as a p53-responsive, proapoptotic factor, but no clear function has been described. Here, we use a nonbiased proteomics approach to identify members of the importin (IMP) family of nuclear transporters as interactors of Ei24 and characteriz...
Autores principales: | Lieu, Kim G., Shim, Eun-Hee, Wang, Jinling, Lokareddy, Ravi K., Tao, Tao, Cingolani, Gino, Zambetti, Gerard P., Jans, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018778/ https://www.ncbi.nlm.nih.gov/pubmed/24821838 http://dx.doi.org/10.1083/jcb.201304055 |
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