Cargando…

Nuclear-Cytoplasmic Partitioning of Cucumber Mosaic Virus Protein 2b Determines the Balance between Its Roles as a Virulence Determinant and an RNA-Silencing Suppressor

The Cucumber Mosaic Virus (CMV) 2b protein is an RNA-silencing suppressor that plays roles in CMV accumulation and virulence. The 2b proteins of subgroup IA CMV strains partition between the nucleus and cytoplasm, but the biological significance of this is uncertain. We fused an additional nuclear l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Zhiyou, Chen, Aizhong, Chen, Wenhu, Liao, Qiansheng, Zhang, Hengmu, Bao, Yiming, Roossinck, Marilyn J., Carr, John P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2014
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019134/ https://www.ncbi.nlm.nih.gov/pubmed/24599997 http://dx.doi.org/10.1128/JVI.00284-14

Ejemplares similares

A New Type of Satellite Associated with Cassava Mosaic Begomoviruses
por: Aimone, Catherine D., et al.
Publicado: (2021)

Two Novel DNAs That Enhance Symptoms and Overcome CMD2 Resistance to Cassava Mosaic Disease
por: Ndunguru, Joseph, et al.
Publicado: (2016)

Multiple Genome Segments Determine Virulence of Bluetongue Virus Serotype 8
por: Janowicz, Anna, et al.
Publicado: (2015)

Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens
por: Zou, Chengcheng, et al.
Publicado: (2019)

Genetic Determinants of Altered Virulence of Type O Foot-and-Mouth Disease Virus
por: Yang, Fan, et al.
Publicado: (2020)

A Single Amino Acid in the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses
por: Bae, Joon-Yong, et al.
Publicado: (2018)

Levels of Influenza A Virus Defective Viral Genomes Determine Pathogenesis in the BALB/c Mouse Model
por: Penn, Rebecca, et al.
Publicado: (2022)

The Pseudoknot Region of the 5′ Untranslated Region Is a Determinant of Viral Tropism and Virulence of Foot-and-Mouth Disease Virus
por: Zhu, Zixiang, et al.
Publicado: (2019)

Ability of the Encephalitic Arbovirus Semliki Forest Virus To Cross the Blood-Brain Barrier Is Determined by the Charge of the E2 Glycoprotein
por: Ferguson, Mhairi C., et al.
Publicado: (2015)

The Human Interferon-Induced MxA Protein Inhibits Early Stages of Influenza A Virus Infection by Retaining the Incoming Viral Genome in the Cytoplasm
por: Xiao, Han, et al.
Publicado: (2013)

CRISPR/Cas9-Constructed Pseudorabies Virus Mutants Reveal the Importance of UL13 in Alphaherpesvirus Escape from Genome Silencing
por: Van Cleemput, Jolien, et al.
Publicado: (2021)

Deletion of both the Tyrosine-Based Endocytosis Signal and the Endoplasmic Reticulum Retrieval Signal in the Cytoplasmic Tail of Spike Protein Attenuates Porcine Epidemic Diarrhea Virus in Pigs
por: Hou, Yixuan, et al.
Publicado: (2019)

A Single Amino Acid at Position 431 of the PB2 Protein Determines the Virulence of H1N1 Swine Influenza Viruses in Mice
por: Xu, Chengzhi, et al.
Publicado: (2020)

HIV-1 Nef Induces Hck/Lyn-Dependent Expansion of Myeloid-Derived Suppressor Cells Associated with Elevated Interleukin-17/G-CSF Levels
por: Priceputu, Elena, et al.
Publicado: (2021)

An improved cucumber mosaic virus-based vector for efficient decoying of plant microRNAs
por: Liao, Qiansheng, et al.
Publicado: (2015)

A Single Amino Acid Substitution in the Novel H7N9 Influenza A Virus NS1 Protein Increases CPSF30 Binding and Virulence
por: Ayllon, Juan, et al.
Publicado: (2014)

Impact of HLA Selection Pressure on HIV Fitness at a Population Level in Mexico and Barbados
por: Juarez-Molina, Claudia I., et al.
Publicado: (2014)

Virus and Host Factors Affecting the Clinical Outcome of Bluetongue Virus Infection
por: Caporale, Marco, et al.
Publicado: (2014)

Acute-Phase CD8 T Cell Responses That Select for Escape Variants Are Needed to Control Live Attenuated Simian Immunodeficiency Virus
por: Harris, Max, et al.
Publicado: (2013)

High Production Rates Sustain In Vivo Levels of PD-1(high) Simian Immunodeficiency Virus-Specific CD8 T Cells in the Face of Rapid Clearance
por: Petrovas, Constantinos, et al.
Publicado: (2013)

Regulatory T Cells Prevent Th2 Immune Responses and Pulmonary Eosinophilia during Respiratory Syncytial Virus Infection in Mice
por: Durant, Lydia R., et al.
Publicado: (2013)

Glycoprotein B Cleavage Is Important for Murid Herpesvirus 4 To Infect Myeloid Cells
por: Glauser, Daniel L., et al.
Publicado: (2013)

Herpes Simplex Virus 1 Targets the Murine Olfactory Neuroepithelium for Host Entry
por: Shivkumar, Maitreyi, et al.
Publicado: (2013)

Immunosuppression Facilitates the Reactivation of Latent Papillomavirus Infections
por: Maglennon, G. A., et al.
Publicado: (2014)

Delayed Sequelae of Neonatal Respiratory Syncytial Virus Infection Are Dependent on Cells of the Innate Immune System
por: Harker, James A., et al.
Publicado: (2014)

Vaccinia Virus Inhibits NF-κB-Dependent Gene Expression Downstream of p65 Translocation
por: Sumner, Rebecca P., et al.
Publicado: (2014)

Respiratory Syncytial Virus Infection, TLR3 Ligands, and Proinflammatory Cytokines Induce CD161 Ligand LLT1 Expression on the Respiratory Epithelium
por: Satkunanathan, Stifani, et al.
Publicado: (2014)

BAFF Receptor Deficiency Limits Gammaherpesvirus Infection
por: Frederico, Bruno, et al.
Publicado: (2014)

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1
por: O'Connor, Geraldine M., et al.
Publicado: (2015)

Tick Saliva Enhances Powassan Virus Transmission to the Host, Influencing Its Dissemination and the Course of Disease
por: Hermance, Meghan E., et al.
Publicado: (2015)

Expanding Regulatory T Cells Alleviates Chikungunya Virus-Induced Pathology in Mice
por: Lee, Wendy W. L., et al.
Publicado: (2015)

Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology
por: Teo, Teck-Hui, et al.
Publicado: (2015)

Glycine at Position 622 in PB1 Contributes to the Virulence of H5N1 Avian Influenza Virus in Mice
por: Feng, Xiaoxiao, et al.
Publicado: (2016)

Tetramer Enrichment Reveals the Presence of Phenotypically Diverse Hepatitis C Virus-Specific CD8(+) T Cells in Chronic Infection
por: Nitschke, Katja, et al.
Publicado: (2014)

Complement Opsonization Promotes Herpes Simplex Virus 2 Infection of Human Dendritic Cells
por: Crisci, Elisa, et al.
Publicado: (2016)

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases
por: Kühn, Nora, et al.
Publicado: (2016)

Primary B Lymphocytes Infected with Kaposi's Sarcoma-Associated Herpesvirus Can Be Expanded In Vitro and Are Recognized by LANA-Specific CD4(+) T Cells
por: Nicol, Samantha M., et al.
Publicado: (2016)

Lymphatic Dissemination of Simian Immunodeficiency Virus after Penile Inoculation
por: Ma, Zhong-Min, et al.
Publicado: (2016)

Leukocyte Immunoglobulin-Like Receptor 1-Expressing Human Natural Killer Cell Subsets Differentially Recognize Isolates of Human Cytomegalovirus through the Viral Major Histocompatibility Complex Class I Homolog UL18
por: Chen, Kevin C., et al.
Publicado: (2016)

Lipopolysaccharide and Tumor Necrosis Factor Alpha Inhibit Interferon Signaling in Hepatocytes by Increasing Ubiquitin-Like Protease 18 (USP18) Expression
por: MacParland, Sonya A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_fq79c4km08vq13inn18h4em024