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Trans-dimerization of JAM-A regulates Rap2 and is mediated by a domain that is distinct from the cis-dimerization interface

Junctional adhesion molecule-A (JAM-A) is a tight junction–associated signaling protein that regulates epithelial cell proliferation, migration, and barrier function. JAM-A dimerization on a common cell surface (in cis) has been shown to regulate cell migration, and evidence suggests that JAM-A may...

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Detalles Bibliográficos
Autores principales: Monteiro, Ana C., Luissint, Anny-Claude, Sumagin, Ronen, Lai, Caroline, Vielmuth, Franziska, Wolf, Mattie F., Laur, Oskar, Reiss, Kerstin, Spindler, Volker, Stehle, Thilo, Dermody, Terence S., Nusrat, Asma, Parkos, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019489/
https://www.ncbi.nlm.nih.gov/pubmed/24672055
http://dx.doi.org/10.1091/mbc.E14-01-0018