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Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins
Nucleophosmin (NPM1) is a multifunctional protein that controls cell growth and genome stability via a mechanism that involves nucleolar–cytoplasmic shuttling. It is clear that NPM1 also contributes to the DNA damage response, yet its exact function is poorly understood. We recently linked NPM1 expr...
Autores principales: | Poletto, Mattia, Lirussi, Lisa, Wilson, David M., Tell, Gianluca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019495/ https://www.ncbi.nlm.nih.gov/pubmed/24648491 http://dx.doi.org/10.1091/mbc.E13-12-0717 |
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