Inhibition of p38 MAPK Signaling Augments Skin Tumorigenesis via NOX2 Driven ROS Generation

p38 mitogen-activated protein kinases (MAPKs) respond to a wide range of extracellular stimuli. While the inhibition of p38 signaling is implicated in the impaired capacity to repair ultraviolet (UV)-induced DNA damage—a primary risk factor for human skin cancers—its mechanism of action in skin carc...

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Detalles Bibliográficos
Autores principales: Liu, Liang, Rezvani, Hamid Reza, Back, Jung Ho, Hosseini, Mohsen, Tang, Xiuwei, Zhu, Yucui, Mahfouf, Walid, Raad, Houssam, Raji, Grace, Athar, Mohammad, Kim, Arianna L., Bickers, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019556/
https://www.ncbi.nlm.nih.gov/pubmed/24824222
http://dx.doi.org/10.1371/journal.pone.0097245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019556/
https://www.ncbi.nlm.nih.gov/pubmed/24824222
http://dx.doi.org/10.1371/journal.pone.0097245

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