Cargando…

Mechanism of Protection by Soluble Epoxide Hydrolase Inhibition in Type 2 Diabetic Stroke

Inhibition of soluble epoxide hydrolase (sEH) is a potential target of therapy for ischemic injury. sEH metabolizes neuroprotective epoxyeicosatrienoic acids (EETs). We recently demonstrated that sEH inhibition reduces infarct size after middle cerebral artery occlusion (MCAO) in type 1 diabetic mic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zuloaga, Kristen L., Krasnow, Stephanie M., Zhu, Xinxia, Zhang, Wenri, Jouihan, Sari A., Shangraw, Robert E., Alkayed, Nabil J., Marks, Daniel L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019567/ https://www.ncbi.nlm.nih.gov/pubmed/24824753 http://dx.doi.org/10.1371/journal.pone.0097529

Ejemplares similares

Soluble Epoxide Hydrolase Blockade after Stroke Onset Protects Normal but Not Diabetic Mice
por: Davis, Catherine M., et al.
Publicado: (2021)

Soluble epoxide hydrolase gene deletion improves blood flow and reduces infarct size after cerebral ischemia in reproductively senescent female mice
por: Zuloaga, Kristen L., et al.
Publicado: (2015)

Role of Endothelial Soluble Epoxide Hydrolase in Cerebrovascular Function and Ischemic Injury
por: Zhang, Wenri, et al.
Publicado: (2013)

Disrupting Dimerization Translocates Soluble Epoxide Hydrolase to Peroxisomes
por: Nelson, Jonathan W., et al.
Publicado: (2016)

Inhibition of Soluble Epoxide Hydrolase for Renal Health
por: Liu, Jun-Yan
Publicado: (2019)

Soluble Epoxide Hydrolase in Atherosclerosis
por: Wang, Yi-Xin Jim, et al.
Publicado: (2010)

Evaluation of fish models of soluble epoxide hydrolase inhibition.
por: Newman, J W, et al.
Publicado: (2001)

Soluble Epoxide Hydrolase and Diabetes Complications
por: Anita, Natasha Z., et al.
Publicado: (2022)

Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice
por: Qin, Jun, et al.
Publicado: (2015)

Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future
por: Park, Bomina, et al.
Publicado: (2019)

Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis
por: McReynolds, Cindy B., et al.
Publicado: (2019)

Inhibition of Soluble Epoxide Hydrolase Activity by Components of Glycyrrhiza uralensis
por: Kim, Jang Hoon, et al.
Publicado: (2023)

Soluble Epoxide Hydrolase Inhibition Protected against Angiotensin II-induced Adventitial Remodeling
por: Zhou, Chi, et al.
Publicado: (2017)

Soluble Epoxide Hydrolase and Brain Cholesterol Metabolism
por: Domingues, Michelle Flores, et al.
Publicado: (2020)

Protective effect of Soluble Epoxide Hydrolase Inhibition in Retinal Vasculopathy associated with Polycystic Kidney Disease
por: Lin, Jihong, et al.
Publicado: (2020)

Research progress on the protective mechanism of a novel soluble epoxide hydrolase inhibitor TPPU on ischemic stroke
por: Huang, Pan
Publicado: (2023)

Soluble epoxide hydrolase inhibition alleviates chemotherapy induced neuropathic pain
por: Takeshita, Ashley A., et al.
Publicado: (2023)

Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors
por: Imig, John D., et al.
Publicado: (2020)

The role of soluble epoxide hydrolase and its inhibitors in depression
por: Borsini, Alessandra
Publicado: (2021)

Impact of SMTP Targeting Plasminogen and Soluble Epoxide Hydrolase on Thrombolysis, Inflammation, and Ischemic Stroke
por: Hasumi, Keiji, et al.
Publicado: (2021)

Inhibition of the Soluble Epoxide Hydrolase Promotes Albuminuria in Mice with Progressive Renal Disease
por: Jung, Oliver, et al.
Publicado: (2010)

Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence
por: Wang, Yuxin, et al.
Publicado: (2021)

Soluble Epoxide Hydrolase Inhibition Prevents Experimental Type 4 Cardiorenal Syndrome
por: Hamzaoui, Mouad, et al.
Publicado: (2021)

Inhibition of Soluble Epoxide Hydrolase Attenuates Bosutinib-Induced Blood Pressure Elevation
por: Cui, Zhen, et al.
Publicado: (2021)

Inhibition of Soluble Epoxide Hydrolase Does Not Promote or Aggravate Pulmonary Hypertension in Rats
por: Leuillier, Matthieu, et al.
Publicado: (2023)

The Metabolism of Epoxyeicosatrienoic Acids by Soluble Epoxide Hydrolase Is Protective against the Development of Vascular Calcification
por: Varennes, Olivier, et al.
Publicado: (2020)

Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors
por: Kodani, Sean D., et al.
Publicado: (2018)

Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation
por: Brenneis, Christian, et al.
Publicado: (2011)

Effects of Soluble Epoxide Hydrolase Deficiency on Acute Pancreatitis in Mice
por: Bettaieb, Ahmed, et al.
Publicado: (2014)

Dysregulation of Soluble Epoxide Hydrolase and Lipidomic Profiles in Anorexia Nervosa
por: Shih, Pei-an Betty, et al.
Publicado: (2015)

Discovery of Novel Soluble Epoxide Hydrolase Inhibitors as Potent Vasodilators
por: Tripathi, Neetika, et al.
Publicado: (2018)

Soluble Epoxide Hydrolase as a Therapeutic Target for Neuropsychiatric Disorders
por: Shan, Jiajing, et al.
Publicado: (2022)

Inhibitory Activity of Quaternary Isoquinoline Alkaloids on Soluble Epoxide Hydrolase
por: Kim, Jang Hoon, et al.
Publicado: (2022)

Soluble epoxide hydrolase inhibitor promotes the healing of oral ulcers
por: Li, Juanjuan, et al.
Publicado: (2023)

Decreased Expression of Soluble Epoxide Hydrolase Suppresses Murine Choroidal Neovascularization
por: Park, Bomina, et al.
Publicado: (2022)

Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Diet-Induced Metabolic Syndrome in Rats
por: Iyer, Abishek, et al.
Publicado: (2012)

Opposite Effects of Gene Deficiency and Pharmacological Inhibition of Soluble Epoxide Hydrolase on Cardiac Fibrosis
por: Li, Lijuan, et al.
Publicado: (2014)

Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia
por: Tu, Ranran, et al.
Publicado: (2018)

The Brain’s Microvascular Response to High Glycemia and to the Inhibition of Soluble Epoxide Hydrolase Is Sexually Dimorphic
por: Nuthikattu, Saivageethi, et al.
Publicado: (2022)

Sex-Specific Response of the Brain Free Oxylipin Profile to Soluble Epoxide Hydrolase Inhibition
por: Norman, Jennifer E., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_422tlb54c934f50mm079619sj1