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NAMPT-Mediated Salvage Synthesis of NAD(+) Controls Morphofunctional Changes of Macrophages

Functional morphodynamic behavior of differentiated macrophages is strongly controlled by actin cytoskeleton rearrangements, a process in which also metabolic cofactors ATP and NAD(H) (i.e. NAD(+) and NADH) and NADP(H) (i.e. NADP(+) and NADPH) play an essential role. Whereas the link to intracellula...

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Detalles Bibliográficos
Autores principales: Venter, Gerda, Oerlemans, Frank T. J. J., Willemse, Marieke, Wijers, Mietske, Fransen, Jack A. M., Wieringa, Bé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019579/
https://www.ncbi.nlm.nih.gov/pubmed/24824795
http://dx.doi.org/10.1371/journal.pone.0097378