Development of Rabbit Monoclonal Antibodies for Detection of Alpha-Dystroglycan in Normal and Dystrophic Tissue

Alpha-dystroglycan requires a rare O-mannose glycan modification to form its binding epitope for extracellular matrix proteins such as laminin. This functional glycan is disrupted in a cohort of muscular dystrophies, the secondary dystroglycanopathies, and is abnormal in some metastatic cancers. The...

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Detalles Bibliográficos
Autores principales: Fortunato, Marisa J., Ball, Charlotte E., Hollinger, Katrin, Patel, Niraj B., Modi, Jill N., Rajasekaran, Vedika, Nonneman, Dan J., Ross, Jason W., Kennedy, Eileen J., Selsby, Joshua T., Beedle, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019581/
https://www.ncbi.nlm.nih.gov/pubmed/24824861
http://dx.doi.org/10.1371/journal.pone.0097567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019581/
https://www.ncbi.nlm.nih.gov/pubmed/24824861
http://dx.doi.org/10.1371/journal.pone.0097567

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