Cargando…

Development of Rabbit Monoclonal Antibodies for Detection of Alpha-Dystroglycan in Normal and Dystrophic Tissue

Alpha-dystroglycan requires a rare O-mannose glycan modification to form its binding epitope for extracellular matrix proteins such as laminin. This functional glycan is disrupted in a cohort of muscular dystrophies, the secondary dystroglycanopathies, and is abnormal in some metastatic cancers. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fortunato, Marisa J., Ball, Charlotte E., Hollinger, Katrin, Patel, Niraj B., Modi, Jill N., Rajasekaran, Vedika, Nonneman, Dan J., Ross, Jason W., Kennedy, Eileen J., Selsby, Joshua T., Beedle, Aaron M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019581/ https://www.ncbi.nlm.nih.gov/pubmed/24824861 http://dx.doi.org/10.1371/journal.pone.0097567

Ejemplares similares

The Small Leucine-Rich Repeat Proteoglycan Biglycan Binds to α-Dystroglycan and Is Upregulated in Dystrophic Muscle
por: Bowe, Mark A., et al.
Publicado: (2000)

ISPD Overexpression Enhances Ribitol-Induced Glycosylation of α-Dystroglycan in Dystrophic FKRP Mutant Mice
por: Cataldi, Marcela P., et al.
Publicado: (2019)

Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with β-dystroglycan
por: Rezniczek, Günther A., et al.
Publicado: (2007)

Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice
por: Cataldi, Marcela P., et al.
Publicado: (2018)

A proteasome inhibitor fails to attenuate dystrophic pathology in mdx mice
por: Selsby, Joshua, et al.
Publicado: (2012)

An Immunological Analysis of Dystroglycan Subunits: Lessons Learned from a Small Cohort of Non-Congenital Dystrophic Patients
por: Pavoni, Ernesto, et al.
Publicado: (2011)

Evidence for a role of dystroglycan regulating the membrane architecture of astroglial endfeet
por: Noell, Susan, et al.
Publicado: (2011)

Long-Term Quercetin Dietary Enrichment Partially Protects Dystrophic Skeletal Muscle
por: Spaulding, Hannah R., et al.
Publicado: (2016)

Abnormal Skeletal Muscle Regeneration plus Mild Alterations in Mature Fiber Type Specification in Fktn-Deficient Dystroglycanopathy Muscular Dystrophy Mice
por: Foltz, Steven J., et al.
Publicado: (2016)

Indicators of increased ER stress and UPR in aged D2-mdx and human dystrophic skeletal muscles
por: Krishna, Swathy, et al.
Publicado: (2023)

Rescue of Dystrophic Skeletal Muscle by PGC-1α Involves a Fast to Slow Fiber Type Shift in the mdx Mouse
por: Selsby, Joshua T., et al.
Publicado: (2012)

Non-muscle alpha-dystroglycan is involved in epithelial development
Publicado: (1995)

The conserved WW-domain binding sites in Dystroglycan C-terminus are essential but partially redundant for Dystroglycan function
por: Yatsenko, AS, et al.
Publicado: (2009)

β-Dystroglycan Restoration and Pathology Progression in the Dystrophic mdx Mouse: Outcome and Implication of a Clinically Oriented Study with a Novel Oral Dasatinib Formulation
por: Mantuano, Paola, et al.
Publicado: (2021)

PGC‐1α overexpression increases transcription factor EB nuclear localization and lysosome abundance in dystrophin‐deficient skeletal muscle
por: Spaulding, Hannah R., et al.
Publicado: (2020)

Distribution of alpha-dystroglycan during embryonic nerve-muscle synaptogenesis
Publicado: (1995)

A dystroglycan ligand in the brain
por: Jegalian, Karin
Publicado: (2001)

γ‐Secretase Dependent Nuclear Targeting of Dystroglycan
por: Leocadio, Daniel, et al.
Publicado: (2016)

Respiratory and cardiac function in congenital muscular dystrophies with alpha dystroglycan deficiency
por: Pane, M., et al.
Publicado: (2012)

An evaluation of the evolution of the gene structure of dystroglycan
por: Brancaccio, Andrea, et al.
Publicado: (2017)

Structural flexibility of human α‐dystroglycan
por: Covaceuszach, Sonia, et al.
Publicado: (2017)

N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on α-dystroglycan and prevents muscular dystrophy
por: Okuma, Hidehiko, et al.
Publicado: (2023)

Dystroglycan versatility in cell adhesion: a tale of multiple motifs
por: Moore, Chris J, et al.
Publicado: (2010)

A stoichiometric complex of neurexins and dystroglycan in brain
por: Sugita, Shuzo, et al.
Publicado: (2001)

Dystroglycan is associated to the disulfide isomerase ERp57
por: Sciandra, Francesca, et al.
Publicado: (2012)

Identification of New Dystroglycan Complexes in Skeletal Muscle
por: Johnson, Eric K., et al.
Publicado: (2013)

Dystroglycan, Tks5 and Src Mediated Assembly of Podosomes in Myoblasts
por: Thompson, Oliver, et al.
Publicado: (2008)

Immunoproteasome Inhibition Ameliorates Aged Dystrophic Mouse Muscle Environment
por: Tripodi, Luana, et al.
Publicado: (2022)

From rabbit antibody repertoires to rabbit monoclonal antibodies
por: Weber, Justus, et al.
Publicado: (2017)

Retrograde trafficking of β-dystroglycan from the plasma membrane to the nucleus
por: Gracida-Jiménez, Viridiana, et al.
Publicado: (2017)

Duplication of the dystroglycan gene in most branches of teleost fish
por: Pavoni, Ernesto, et al.
Publicado: (2007)

Acetylcholinesterase Clustering at the Neuromuscular Junction Involves Perlecan and Dystroglycan
por: Peng, H. Benjamin, et al.
Publicado: (1999)

Functional Glycosylation of Dystroglycan Is Crucial for Thymocyte Development in the Mouse
por: Liou, Li-Ying, et al.
Publicado: (2010)

Dystroglycan controls dendritic morphogenesis of hippocampal neurons in vitro
por: Bijata, Monika, et al.
Publicado: (2015)

Genetic Engineering of Dystroglycan in Animal Models of Muscular Dystrophy
por: Sciandra, Francesca, et al.
Publicado: (2015)

Structural basis of laminin binding to the LARGE glycans on dystroglycan
por: Briggs, David C., et al.
Publicado: (2016)

Dystroglycan is a scaffold for extracellular axon guidance decisions
por: Lindenmaier, L Bailey, et al.
Publicado: (2019)

Regulation of Dystroglycan Gene Expression in Early Myoblast Differentiation
por: Hamed, Munerah, et al.
Publicado: (2022)

Identification of Matriglycan by Dual Exoglycosidase Digestion of α-Dystroglycan
por: Chandel, Ishita, et al.
Publicado: (2023)

Emerging Therapies for Dystrophic Cardiomyopathy
por: Garry, Daniel J., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m7mr9mdpdqu4f41m2mrf9alclv