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A Note on Exact Differences between Beta Distributions in Genomic (Methylation) Studies
We apply a known algorithm for computing exactly inequalities between Beta distributions to assess whether a given position in a genome is differentially methylated across samples. We discuss the advantages brought by the adoption of this solution with respect to two approximations (Fisher's te...
Autores principales: | Raineri, Emanuele, Dabad, Marc, Heath, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019606/ https://www.ncbi.nlm.nih.gov/pubmed/24824426 http://dx.doi.org/10.1371/journal.pone.0097349 |
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