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Links between nucleolar activity, rDNA stability, aneuploidy and chronological aging in the yeast Saccharomyces cerevisiae
The nucleolus is speculated to be a regulator of cellular senescence in numerous biological systems (Guarente, Genes Dev 11(19):2449–2455, 1997; Johnson et al., Curr Opin Cell Biol 10(3):332–338, 1998). In the budding yeast Saccharomyces cerevisiae, alterations in nucleolar architecture, the redistr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019837/ https://www.ncbi.nlm.nih.gov/pubmed/24711086 http://dx.doi.org/10.1007/s10522-014-9499-y |