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Links between nucleolar activity, rDNA stability, aneuploidy and chronological aging in the yeast Saccharomyces cerevisiae

The nucleolus is speculated to be a regulator of cellular senescence in numerous biological systems (Guarente, Genes Dev 11(19):2449–2455, 1997; Johnson et al., Curr Opin Cell Biol 10(3):332–338, 1998). In the budding yeast Saccharomyces cerevisiae, alterations in nucleolar architecture, the redistr...

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Detalles Bibliográficos
Autores principales: Lewinska, Anna, Miedziak, Beata, Kulak, Klaudia, Molon, Mateusz, Wnuk, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019837/
https://www.ncbi.nlm.nih.gov/pubmed/24711086
http://dx.doi.org/10.1007/s10522-014-9499-y