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Statistical issues and challenges in immuno-oncology
BACKGROUND: The development of immuno-oncologic agents poses unique challenges, namely that both efficacy and safety profiles differ from previously characterized cytotoxic and pathway-specific agents. In addition, exponential distribution is usually assumed in study designs with time-to-event endpo...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019889/ https://www.ncbi.nlm.nih.gov/pubmed/24829754 http://dx.doi.org/10.1186/2051-1426-1-18 |