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Very small size proteoliposomes abrogate cross-presentation of tumor antigens by myeloid-derived suppressor cells and induce their differentiation to dendritic cells

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are among the major obstacles that adjuvants for cancer vaccines have to overcome. These cells cross-present tumor-associated antigens (TAA) to naive T lymphocytes with a tolerogenic outcome. Very Small Size Proteoliposomes (VSSP) is used as adjuv...

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Detalles Bibliográficos
Autores principales:	Fernández, Audry, Oliver, Liliana, Alvarez, Rydell, Hernández, Arletty, Raymond, Judith, Fernández, Luis E, Mesa, Circe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019907/ https://www.ncbi.nlm.nih.gov/pubmed/24829762 http://dx.doi.org/10.1186/2051-1426-2-5

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