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PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis

Double-stranded RNA-dependent protein kinase (PKR) regulates antiviral activity, immune responses, apoptosis and neurotoxicity. Gliatropic coronavirus infection induced PKR activation in infected as well uninfected cells within the central nervous system (CNS). However, PKR deficiency only modestly...

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Detalles Bibliográficos
Autores principales: Kapil, Parul, Stohlman, Stephen A., Hinton, David R., Bergmann, Cornelia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019976/
https://www.ncbi.nlm.nih.gov/pubmed/24642385
http://dx.doi.org/10.1016/j.jneuroim.2014.02.012

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