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Myoplasmic resting Ca(2+) regulation by ryanodine receptors is under the control of a novel Ca(2+)-binding region of the receptor

Passive SR (sarcoplasmic reticulum) Ca(2+) leak through the RyR (ryanodine receptor) plays a critical role in the mechanisms that regulate [Ca(2+)](rest) (intracellular resting myoplasmic free Ca(2+) concentration) in muscle. This process appears to be isoform-specific as expression of either RyR1 o...

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Detalles Bibliográficos
Autores principales: Chen, Yanyi, Xue, Shenghui, Zou, Juan, Lopez, Jose R., Yang, Jenny J., Perez, Claudio F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019983/
https://www.ncbi.nlm.nih.gov/pubmed/24635445
http://dx.doi.org/10.1042/BJ20131553