Animal Models of C-Reactive Protein

As the main theme of this special issue, CRP not only is an inflammatory marker but also has diverse biological functions associated with different diseases. To investigate CRP's physiologies and their relationship with human pathological significance, it is essential to use appropriate animal...

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Detalles Bibliográficos
Autores principales: Torzewski, Michael, Waqar, Ahmed Bilal, Fan, Jianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020216/
https://www.ncbi.nlm.nih.gov/pubmed/24872599
http://dx.doi.org/10.1155/2014/683598
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author Torzewski, Michael
Waqar, Ahmed Bilal
Fan, Jianglin
author_facet Torzewski, Michael
Waqar, Ahmed Bilal
Fan, Jianglin
author_sort Torzewski, Michael
collection PubMed
description As the main theme of this special issue, CRP not only is an inflammatory marker but also has diverse biological functions associated with different diseases. To investigate CRP's physiologies and their relationship with human pathological significance, it is essential to use appropriate animal models for translational research. The most popular models for the study of CRP are transgenic mice. However, researchers should be careful when extrapolating the findings derived from these animal models. This review will discuss the current concerns on CRP transgenic mice and rabbits.
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spelling pubmed-40202162014-05-28 Animal Models of C-Reactive Protein Torzewski, Michael Waqar, Ahmed Bilal Fan, Jianglin Mediators Inflamm Review Article As the main theme of this special issue, CRP not only is an inflammatory marker but also has diverse biological functions associated with different diseases. To investigate CRP's physiologies and their relationship with human pathological significance, it is essential to use appropriate animal models for translational research. The most popular models for the study of CRP are transgenic mice. However, researchers should be careful when extrapolating the findings derived from these animal models. This review will discuss the current concerns on CRP transgenic mice and rabbits. Hindawi Publishing Corporation 2014 2014-04-24 /pmc/articles/PMC4020216/ /pubmed/24872599 http://dx.doi.org/10.1155/2014/683598 Text en Copyright © 2014 Michael Torzewski et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Torzewski, Michael
Waqar, Ahmed Bilal
Fan, Jianglin
Animal Models of C-Reactive Protein
title Animal Models of C-Reactive Protein
title_full Animal Models of C-Reactive Protein
title_fullStr Animal Models of C-Reactive Protein
title_full_unstemmed Animal Models of C-Reactive Protein
title_short Animal Models of C-Reactive Protein
title_sort animal models of c-reactive protein
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020216/
https://www.ncbi.nlm.nih.gov/pubmed/24872599
http://dx.doi.org/10.1155/2014/683598
work_keys_str_mv AT torzewskimichael animalmodelsofcreactiveprotein
AT waqarahmedbilal animalmodelsofcreactiveprotein
AT fanjianglin animalmodelsofcreactiveprotein

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