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H3K4 demethylase activities repress proliferative and postmitotic aging

Homeostasis of postmitotic and proliferating cells is maintained by pathways that repress stress. We found that the Caenorhabditis elegans histone 3 lysine 4 (H3K4) demethylases RBR-2 and SPR-5 promoted postmitotic longevity of stress-resistant daf-2 adults, altered pools of methylated H3K4, and pro...

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Detalles Bibliográficos
Autores principales:	Alvares, Stacy M, Mayberry, Gaea A, Joyner, Ebony Y, Lakowski, Bernard, Ahmed, Shawn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020274/ https://www.ncbi.nlm.nih.gov/pubmed/24134677 http://dx.doi.org/10.1111/acel.12166

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