Chrysophanol Inhibits NALP3 Inflammasome Activation and Ameliorates Cerebral Ischemia/Reperfusion in Mice

The most effective way to contain cerebral ischemic injury is reperfusion; however, reperfusion itself may result in tissue injury, for which inflammatory damage is one of the main causative factors. NALP3 inflammasome is a multiprotein complex. It consists of NALP3, ASC, and caspase-1, whose functi...

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Detalles Bibliográficos
Autores principales: Zhang, Nan, Zhang, Xiangjian, Liu, Xiaoxia, Wang, Hong, Xue, Jing, Yu, Jingying, Kang, Ning, Wang, Xiaolu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020303/
https://www.ncbi.nlm.nih.gov/pubmed/24876671
http://dx.doi.org/10.1155/2014/370530

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