COX-2 Gene Promoter Methylation in Patients Infected with Helicobacter Pylori

Cyclooxygenase (COX) plays a critical role in peptic ulcer development. COX-2 contains CpG islands in promoter area, which suggests possible epigenetic mechanisms of gene silencing. We evaluated COX-2 gene promoter methylation levels in the gastric mucosa of patients with various gastric diseases. D...

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Detalles Bibliográficos
Autores principales: Michikawa, Yosuke, Yasuda, Hiroshi, Watanabe, Yoshiyuki, Oikawa, Ritsuko, Ohishi, Yoshichika, Maehata, Tadateru, Itoh, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020401/
https://www.ncbi.nlm.nih.gov/pubmed/24833939
http://dx.doi.org/10.4137/CGast.S11917

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