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Neurological Effects of Honey: Current and Future Prospects

Honey is the only insect-derived natural product with therapeutic, traditional, spiritual, nutritional, cosmetic, and industrial value. In addition to having excellent nutritional value, honey is a good source of physiologically active natural compounds, such as polyphenols. Unfortunately, there are...

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Detalles Bibliográficos
Autores principales: Mijanur Rahman, Mohammad, Gan, Siew Hua, Khalil, Md. Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020454/
https://www.ncbi.nlm.nih.gov/pubmed/24876885
http://dx.doi.org/10.1155/2014/958721
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author Mijanur Rahman, Mohammad
Gan, Siew Hua
Khalil, Md. Ibrahim
author_facet Mijanur Rahman, Mohammad
Gan, Siew Hua
Khalil, Md. Ibrahim
author_sort Mijanur Rahman, Mohammad
collection PubMed
description Honey is the only insect-derived natural product with therapeutic, traditional, spiritual, nutritional, cosmetic, and industrial value. In addition to having excellent nutritional value, honey is a good source of physiologically active natural compounds, such as polyphenols. Unfortunately, there are very few current research projects investigating the nootropic and neuropharmacological effects of honey, and these are still in their early stages. Raw honey possesses nootropic effects, such as memory-enhancing effects, as well as neuropharmacological activities, such as anxiolytic, antinociceptive, anticonvulsant, and antidepressant activities. Research suggests that the polyphenol constituents of honey can quench biological reactive oxygen species and counter oxidative stress while restoring the cellular antioxidant defense system. Honey polyphenols are also directly involved in apoptotic activities while attenuating microglia-induced neuroinflammation. Honey polyphenols are useful in improving memory deficits and can act at the molecular level. Therefore, the ultimate biochemical impact of honey on specific neurodegenerative diseases, apoptosis, necrosis, neuroinflammation, synaptic plasticity, and behavior-modulating neural circuitry should be evaluated with appropriate mechanistic approaches using biochemical and molecular tools.
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spelling pubmed-40204542014-05-29 Neurological Effects of Honey: Current and Future Prospects Mijanur Rahman, Mohammad Gan, Siew Hua Khalil, Md. Ibrahim Evid Based Complement Alternat Med Review Article Honey is the only insect-derived natural product with therapeutic, traditional, spiritual, nutritional, cosmetic, and industrial value. In addition to having excellent nutritional value, honey is a good source of physiologically active natural compounds, such as polyphenols. Unfortunately, there are very few current research projects investigating the nootropic and neuropharmacological effects of honey, and these are still in their early stages. Raw honey possesses nootropic effects, such as memory-enhancing effects, as well as neuropharmacological activities, such as anxiolytic, antinociceptive, anticonvulsant, and antidepressant activities. Research suggests that the polyphenol constituents of honey can quench biological reactive oxygen species and counter oxidative stress while restoring the cellular antioxidant defense system. Honey polyphenols are also directly involved in apoptotic activities while attenuating microglia-induced neuroinflammation. Honey polyphenols are useful in improving memory deficits and can act at the molecular level. Therefore, the ultimate biochemical impact of honey on specific neurodegenerative diseases, apoptosis, necrosis, neuroinflammation, synaptic plasticity, and behavior-modulating neural circuitry should be evaluated with appropriate mechanistic approaches using biochemical and molecular tools. Hindawi Publishing Corporation 2014 2014-04-27 /pmc/articles/PMC4020454/ /pubmed/24876885 http://dx.doi.org/10.1155/2014/958721 Text en Copyright © 2014 Mohammad Mijanur Rahman et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Mijanur Rahman, Mohammad
Gan, Siew Hua
Khalil, Md. Ibrahim
Neurological Effects of Honey: Current and Future Prospects
title Neurological Effects of Honey: Current and Future Prospects
title_full Neurological Effects of Honey: Current and Future Prospects
title_fullStr Neurological Effects of Honey: Current and Future Prospects
title_full_unstemmed Neurological Effects of Honey: Current and Future Prospects
title_short Neurological Effects of Honey: Current and Future Prospects
title_sort neurological effects of honey: current and future prospects
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020454/
https://www.ncbi.nlm.nih.gov/pubmed/24876885
http://dx.doi.org/10.1155/2014/958721
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