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Werner syndrome protein positively regulates XRCC4-like factor transcription
XRCC4-like factor (XLF) is involved in non-homologous end joining-mediated repair of DNA double-strand breaks (DSBs). Mutations in the WRN gene results in the development of Werner syndrome (WS), a rare autosomal recessive disorder characterized by premature ageing and genome instability. In the pre...
Autores principales: | LIU, DONGYUN, DENG, XIAOLI, YUAN, CHONGZHEN, CHEN, LIN, CONG, YUSHENG, XU, XINGZHI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020486/ https://www.ncbi.nlm.nih.gov/pubmed/24626809 http://dx.doi.org/10.3892/mmr.2014.2030 |
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