Cargando…

Werner syndrome protein positively regulates XRCC4-like factor transcription

XRCC4-like factor (XLF) is involved in non-homologous end joining-mediated repair of DNA double-strand breaks (DSBs). Mutations in the WRN gene results in the development of Werner syndrome (WS), a rare autosomal recessive disorder characterized by premature ageing and genome instability. In the pre...

Descripción completa

Detalles Bibliográficos
Autores principales: LIU, DONGYUN, DENG, XIAOLI, YUAN, CHONGZHEN, CHEN, LIN, CONG, YUSHENG, XU, XINGZHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020486/
https://www.ncbi.nlm.nih.gov/pubmed/24626809
http://dx.doi.org/10.3892/mmr.2014.2030

Ejemplares similares