Severe Pulmonary Suppuration with Infection-Induced Systemic Inflammatory Response Syndrome following Tongue Cancer Surgery in a Patient Undergoing Tocilizumab Therapy for Rheumatoid Arthritis

A 65-year-old woman with rheumatoid arthritis treated by tocilizumab (TCZ) presented with tongue squamous cell carcinoma. While surgery was performed without any complications the aspiration pneumonia rapidly worsened by postoperative day 2 and severe pulmonary suppuration in the right lung field wi...

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Autores principales: Yamagata, Kenji, Shimojo, Nobutake, Ito, Hiroyuki, Ijima, Junya, Hasegawa, Shogo, Yanagawa, Toru, Mizutani, Taro, Bukawa, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020557/
https://www.ncbi.nlm.nih.gov/pubmed/24872899
http://dx.doi.org/10.1155/2014/649086
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author Yamagata, Kenji
Shimojo, Nobutake
Ito, Hiroyuki
Ijima, Junya
Hasegawa, Shogo
Yanagawa, Toru
Mizutani, Taro
Bukawa, Hiroki
author_facet Yamagata, Kenji
Shimojo, Nobutake
Ito, Hiroyuki
Ijima, Junya
Hasegawa, Shogo
Yanagawa, Toru
Mizutani, Taro
Bukawa, Hiroki
author_sort Yamagata, Kenji
collection PubMed
description A 65-year-old woman with rheumatoid arthritis treated by tocilizumab (TCZ) presented with tongue squamous cell carcinoma. While surgery was performed without any complications the aspiration pneumonia rapidly worsened by postoperative day 2 and severe pulmonary suppuration in the right lung field with infection-induced systemic inflammatory response syndrome (SIRS) was diagnosed. Antibiotic and respirator treatment improved her condition. The anti-inflammatory effect of TCZ may mask the symptoms and signs of severe infection with SIRS.
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spelling pubmed-40205572014-05-28 Severe Pulmonary Suppuration with Infection-Induced Systemic Inflammatory Response Syndrome following Tongue Cancer Surgery in a Patient Undergoing Tocilizumab Therapy for Rheumatoid Arthritis Yamagata, Kenji Shimojo, Nobutake Ito, Hiroyuki Ijima, Junya Hasegawa, Shogo Yanagawa, Toru Mizutani, Taro Bukawa, Hiroki Case Rep Dent Case Report A 65-year-old woman with rheumatoid arthritis treated by tocilizumab (TCZ) presented with tongue squamous cell carcinoma. While surgery was performed without any complications the aspiration pneumonia rapidly worsened by postoperative day 2 and severe pulmonary suppuration in the right lung field with infection-induced systemic inflammatory response syndrome (SIRS) was diagnosed. Antibiotic and respirator treatment improved her condition. The anti-inflammatory effect of TCZ may mask the symptoms and signs of severe infection with SIRS. Hindawi Publishing Corporation 2014 2014-04-29 /pmc/articles/PMC4020557/ /pubmed/24872899 http://dx.doi.org/10.1155/2014/649086 Text en Copyright © 2014 Kenji Yamagata et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yamagata, Kenji
Shimojo, Nobutake
Ito, Hiroyuki
Ijima, Junya
Hasegawa, Shogo
Yanagawa, Toru
Mizutani, Taro
Bukawa, Hiroki
Severe Pulmonary Suppuration with Infection-Induced Systemic Inflammatory Response Syndrome following Tongue Cancer Surgery in a Patient Undergoing Tocilizumab Therapy for Rheumatoid Arthritis
title Severe Pulmonary Suppuration with Infection-Induced Systemic Inflammatory Response Syndrome following Tongue Cancer Surgery in a Patient Undergoing Tocilizumab Therapy for Rheumatoid Arthritis
title_full Severe Pulmonary Suppuration with Infection-Induced Systemic Inflammatory Response Syndrome following Tongue Cancer Surgery in a Patient Undergoing Tocilizumab Therapy for Rheumatoid Arthritis
title_fullStr Severe Pulmonary Suppuration with Infection-Induced Systemic Inflammatory Response Syndrome following Tongue Cancer Surgery in a Patient Undergoing Tocilizumab Therapy for Rheumatoid Arthritis
title_full_unstemmed Severe Pulmonary Suppuration with Infection-Induced Systemic Inflammatory Response Syndrome following Tongue Cancer Surgery in a Patient Undergoing Tocilizumab Therapy for Rheumatoid Arthritis
title_short Severe Pulmonary Suppuration with Infection-Induced Systemic Inflammatory Response Syndrome following Tongue Cancer Surgery in a Patient Undergoing Tocilizumab Therapy for Rheumatoid Arthritis
title_sort severe pulmonary suppuration with infection-induced systemic inflammatory response syndrome following tongue cancer surgery in a patient undergoing tocilizumab therapy for rheumatoid arthritis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020557/
https://www.ncbi.nlm.nih.gov/pubmed/24872899
http://dx.doi.org/10.1155/2014/649086
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