Ageing combines CD4 T cell lymphopenia in secondary lymphoid organs and T cell accumulation in gut associated lymphoid tissue

BACKGROUND: CD4 T cell lymphopenia is an important T cell defect associated to ageing. Higher susceptibility to infections, cancer, or autoimmune pathologies described in aged individuals is thought to partly rely on T cell lymphopenia. We hypothesize that such diverse effects may reflect anatomical...

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Detalles Bibliográficos
Autores principales: Martinet, Kim Zita, Bloquet, Stéphane, Bourgeois, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020584/
https://www.ncbi.nlm.nih.gov/pubmed/24829607
http://dx.doi.org/10.1186/1742-4933-11-8

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