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A simplified up-down method (SUDO) for measuring mechanical nociception in rodents using von Frey filaments
BACKGROUND: The measurement of mechanosensitivity is a key method for the study of pain in animal models. This is often accomplished with the use of von Frey filaments in an up-down testing paradigm. The up-down method described by Chaplan et al. (J Neurosci Methods 53:55–63, 1994) for mechanosensit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020614/ https://www.ncbi.nlm.nih.gov/pubmed/24739328 http://dx.doi.org/10.1186/1744-8069-10-26 |