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Transcriptome-Based Analysis of Kidney Gene Expression Changes Associated with Diabetes in OVE26 Mice, in the Presence and Absence of Losartan Treatment

Diabetes is among the most common causes of end-stage renal disease, although its pathophysiology is incompletely understood. We performed next-generation sequencing-based transcriptome analysis of renal gene expression changes in the OVE26 murine model of diabetes (age 15 weeks), relative to non-di...

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Detalles Bibliográficos
Autores principales: Komers, Radko, Xu, Bei, Fu, Yi, McClelland, Aaron, Kantharidis, Phillip, Mittal, Amit, Cohen, Herbert T., Cohen, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020814/
https://www.ncbi.nlm.nih.gov/pubmed/24827579
http://dx.doi.org/10.1371/journal.pone.0096987