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Transcriptome-Based Analysis of Kidney Gene Expression Changes Associated with Diabetes in OVE26 Mice, in the Presence and Absence of Losartan Treatment
Diabetes is among the most common causes of end-stage renal disease, although its pathophysiology is incompletely understood. We performed next-generation sequencing-based transcriptome analysis of renal gene expression changes in the OVE26 murine model of diabetes (age 15 weeks), relative to non-di...
Autores principales: | Komers, Radko, Xu, Bei, Fu, Yi, McClelland, Aaron, Kantharidis, Phillip, Mittal, Amit, Cohen, Herbert T., Cohen, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020814/ https://www.ncbi.nlm.nih.gov/pubmed/24827579 http://dx.doi.org/10.1371/journal.pone.0096987 |
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