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Loss of Central Auditory Processing in a Mouse Model of Canavan Disease

Canavan Disease (CD) is a leukodystrophy caused by homozygous null mutations in the gene encoding aspartoacylase (ASPA). ASPA-deficiency is characterized by severe psychomotor retardation, and excessive levels of the ASPA substrate N-acetylaspartate (NAA). ASPA is an oligodendrocyte marker and it is...

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Detalles Bibliográficos
Autores principales:	von Jonquieres, Georg, Froud, Kristina E., Klugmann, Claudia B., Wong, Ann C. Y., Housley, Gary D., Klugmann, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020830/ https://www.ncbi.nlm.nih.gov/pubmed/24826990 http://dx.doi.org/10.1371/journal.pone.0097374

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