Cargando…
Toll-Like Receptor-4 deficiency enhances repair of ultraviolet radiation induced cutaneous DNA damage by nucleotide excision repair mechanism
UVB-induced DNA damage plays a critical role in development of photoimmunosuppression. The purpose of this study was to determine whether repair of UVB-induced DNA damage is regulated by Toll-like receptor-4 (TLR4). When TLR4 gene knockout (TLR4(-/-)) and TLR4 competent (TLR4(+/+)) mice were subject...
Autores principales: | Ahmad, Israr, Simanyi, Eva, Guroji, Purushotham, Tamimi, Iman A, delaRosa, Hillary J, Nagar, Anusuiya, Nagar, Priyamvada, Katiyar, Santosh K, Elmets, Craig A, Yusuf, Nabiha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020975/ https://www.ncbi.nlm.nih.gov/pubmed/24326454 http://dx.doi.org/10.1038/jid.2013.530 |
Ejemplares similares
-
Toll-Like Receptor-4 Antagonist Enhances the Repair of Ultraviolet Radiation-Induced DNA Damage and Augments Anti-Tumor Immune Responses in Mice
por: Sherwani, Mohammad Asif, et al.
Publicado: (2021) -
Type I Interferons Enhance the Repair of Ultraviolet Radiation-Induced DNA Damage and Regulate Cutaneous Immune Suppression
por: Sherwani, Mohammad Asif, et al.
Publicado: (2022) -
Silymarin Protects Epidermal Keratinocytes from Ultraviolet Radiation-Induced Apoptosis and DNA Damage by Nucleotide Excision Repair Mechanism
por: Katiyar, Santosh K., et al.
Publicado: (2011) -
In vitro evaluation of anti-proliferative, anti-inflammatory and pro-apoptotic activities of the methanolic extracts of Andrographis nallamalayana Ellis on A375 and B16F10 melanoma cell lines
por: Purushotham, Guroji, et al.
Publicado: (2016) -
IL-17 Mediated Inflammation Promotes Tumor Growth and Progression in the Skin
por: He, Donggou, et al.
Publicado: (2012)