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Novel nikkomycin analogues generated by mutasynthesis in Streptomyces ansochromogenes
BACKGROUND: Nikkomycins are competitive inhibitors of chitin synthase and inhibit the growth of filamentous fungi, insects, acarids and yeasts. The gene cluster responsible for biosynthesis of nikkomycins has been cloned and the biosynthetic pathway was elucidated at the genetic, enzymatic and regul...
Autores principales: | Feng, Chi, Ling, Hongbo, Du, Deyao, Zhang, Jihui, Niu, Guoqing, Tan, Huarong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021061/ https://www.ncbi.nlm.nih.gov/pubmed/24751325 http://dx.doi.org/10.1186/1475-2859-13-59 |
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