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High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer

BACKGROUND: STAT1 has been attributed a function as tumor suppressor. However, in breast cancer data from microarray analysis indicated a predictive value of high mRNA expression levels of STAT1 and STAT1 target genes belonging to the interferon-related signature for a poor response to therapy. To c...

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Detalles Bibliográficos
Autores principales:	Tymoszuk, Piotr, Charoentong, Pornpimol, Hackl, Hubert, Spilka, Rita, Müller-Holzner, Elisabeth, Trajanoski, Zlatko, Obrist, Peter, Revillion, Françoise, Peyrat, Jean-Philippe, Fiegl, Heidi, Doppler, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021106/ https://www.ncbi.nlm.nih.gov/pubmed/24725474 http://dx.doi.org/10.1186/1471-2407-14-257

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