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Emerging modes of PINK1 signaling: another task for MARK2
PTEN-induced kinase 1 (PINK1) acts at multiple levels to promote mitochondrial health, including regulatory influence on ATP-synthesis, protein quality control, apoptosis, mitochondrial transport, and destiny. PINK1 mutations are linked to Parkinson disease (PD) and mostly result in loss of kinase a...
Autores principales: | Matenia, Dorthe, Mandelkow, Eva M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021145/ https://www.ncbi.nlm.nih.gov/pubmed/24847206 http://dx.doi.org/10.3389/fnmol.2014.00037 |
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