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Transient protein-protein interface prediction: datasets, features, algorithms, and the RAD-T predictor

BACKGROUND: Transient protein-protein interactions (PPIs), which underly most biological processes, are a prime target for therapeutic development. Immense progress has been made towards computational prediction of PPIs using methods such as protein docking and sequence analysis. However, docking ge...

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Detalles Bibliográficos
Autores principales: Bendell, Calem J, Liu, Shalon, Aumentado-Armstrong, Tristan, Istrate, Bogdan, Cernek, Paul T, Khan, Samuel, Picioreanu, Sergiu, Zhao, Michael, Murgita, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021185/
https://www.ncbi.nlm.nih.gov/pubmed/24661439
http://dx.doi.org/10.1186/1471-2105-15-82