Cargando…

Conformational changes and translocation of tissue-transglutaminase to the plasma membranes: role in cancer cell migration

BACKGROUND: Tissue-transglutaminase (TG2), a dual function G-protein, plays key roles in cell differentiation and migration. In our previous studies we reported the mechanism of TG2-induced cell differentiation. In present study, we explored the mechanism of how TG2 may be involved in cell migration...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Ambrish, Hu, Jianjun, LaVoie, Holly A, Walsh, Kenneth B, DiPette, Donald J, Singh, Ugra S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021189/ https://www.ncbi.nlm.nih.gov/pubmed/24725450 http://dx.doi.org/10.1186/1471-2407-14-256

Ejemplares similares

Erratum to: Conformational changes and translocation of tissue-transglutaminase to the plasma membranes: role in cancer cell migration
por: Kumar, Ambrish, et al.
Publicado: (2016)

Ethanol Neurotoxicity in the Developing Cerebellum: Underlying Mechanisms and Implications
por: Kumar, Ambrish, et al.
Publicado: (2013)

Sparstolonin B, a Novel Plant Derived Compound, Arrests Cell Cycle and Induces Apoptosis in N-Myc Amplified and N-Myc Nonamplified Neuroblastoma Cells
por: Kumar, Ambrish, et al.
Publicado: (2014)

Correction: Sparstolonin B, a Novel Plant Derived Compound, Arrests Cell Cycle and Induces Apoptosis in N-Myc Amplified and N-Myc Nonamplified Neuroblastoma Cells
por: Kumar, Ambrish, et al.
Publicado: (2016)

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma
por: Kumar, Ambrish, et al.
Publicado: (2014)

Correction: Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma
por: Kumar, Ambrish, et al.
Publicado: (2016)

Protective Role of α-Calcitonin Gene-Related Peptide in Cardiovascular Diseases
por: Kumar, Ambrish, et al.
Publicado: (2019)

Alpha‐calcitonin gene‐related peptide prevents pressure‐overload induced heart failure: role of apoptosis and oxidative stress
por: Kumar, Ambrish, et al.
Publicado: (2019)

A Novel Alginate-Based Delivery System for the Prevention and Treatment of Pressure-Overload Induced Heart Failure
por: Kumar, Ambrish, et al.
Publicado: (2021)

Alpha-Calcitonin Gene Related Peptide: New Therapeutic Strategies for the Treatment and Prevention of Cardiovascular Disease and Migraine
por: Kumar, Ambrish, et al.
Publicado: (2022)

Approaches to the Management of Hypertension in Resource-Limited Settings: Strategies to Overcome the Hypertension Crisis in the Post-COVID Era
por: Skeete, Jamario, et al.
Publicado: (2020)

Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin
por: Charan, R A, et al.
Publicado: (2014)

Protective effect of resveratrol against pressure overload-induced heart failure
por: Gupta, Prakash K, et al.
Publicado: (2014)

Sex‐based differences in hypertension: Understanding the trends
por: Skeete, Jamario, et al.
Publicado: (2021)

Inadequate hypertension control rates: A global concern for countries of all income levels
por: Edwards, Elizabeth W., et al.
Publicado: (2022)

Cardiac structure and function in resistant hypertension: The beneficial role of blood pressure control
por: Mehta, Neil D., et al.
Publicado: (2023)

HEARTS in the Americas appraisal checklist and clinical pathway for comprehensive hypertension management in primary care
por: Rosende, Andres, et al.
Publicado: (2022)

Self‐measurement of blood pressure in the workplace: An expansion of out‐of‐office blood pressure measurements to unmask masked hypertension
por: Giordano, Jacob, et al.
Publicado: (2021)

Is there a special relationship between complex I activity and nigral neuronal loss in Parkinson’s disease? A critical reappraisal
por: Subrahmanian, Nitya, et al.
Publicado: (2021)

Transglutaminase 2 Undergoes a Large Conformational Change upon Activation
por: Pinkas, Daniel M, et al.
Publicado: (2007)

Intracellular Localization and Conformational State of Transglutaminase 2: Implications for Cell Death
por: Gundemir, Soner, et al.
Publicado: (2009)

Sulfated glycosaminoglycans inhibit transglutaminase 2 by stabilizing its closed conformation
por: Müller, Claudia Damaris, et al.
Publicado: (2022)

The Impact of N(ε)-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2
por: Heerwig, Andreas, et al.
Publicado: (2023)

A small molecule regulator of tissue transglutaminase conformation inhibits the malignant phenotype of cancer cells
por: Katt, William P., et al.
Publicado: (2018)

Opening up about Tissue Transglutaminase: When Conformation Matters More than Enzymatic Activity
por: Katt, William P., et al.
Publicado: (2018)

Transcriptional responses of Escherichia coli during recovery from inorganic or organic mercury exposure
por: LaVoie, Stephen P., et al.
Publicado: (2018)

Correction to: Transcriptional responses of Escherichia coli during recovery from inorganic or organic mercury exposure
por: LaVoie, Stephen P., et al.
Publicado: (2018)

Different conformations of nascent polypeptides during translocation across the ER membrane
por: Mingarro, Ismael, et al.
Publicado: (2000)

Allosteric Activation of Transglutaminase 2 via Inducing an “Open” Conformation for Osteoblast Differentiation
por: Yang, Zhuo, et al.
Publicado: (2023)

Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3
por: Heggelund, Julie Elisabeth, et al.
Publicado: (2023)

Degree of handedness and priming: further evidence for a distinction between production and identification priming mechanisms
por: LaVoie, Donna J., et al.
Publicado: (2015)

Developing population-based hypertension control programs
por: Jaffe, Marc G., et al.
Publicado: (2022)

Transglutaminase 2 Promotes Migration and Invasion of Lung Cancer Cells
por: Lee, Hung-Tsung, et al.
Publicado: (2018)

Astrocyte-Derived Tissue Transglutaminase Interacts with Fibronectin: A Role in Astrocyte Adhesion and Migration?
por: van Strien, Miriam E., et al.
Publicado: (2011)

Tissue Transglutaminase but Not Microbial Transglutaminase Is Inhibited by Exogenous Oxidative Substances in Celiac Disease
por: Stricker, Sebastian, et al.
Publicado: (2022)

RhoA vesicle trafficking–mediated transglutaminase 2 membrane translocation promotes IgA1 mesangial deposition in IgA nephropathy
por: Zhong, Zhong, et al.
Publicado: (2023)

Religious Coping Amidst a Pandemic: Impact on COVID-19-Related Anxiety
por: DeRossett, Tommy, et al.
Publicado: (2021)

HEARTS in the Americas clinical pathway. Strengthening the decision support system to improve hypertension and cardiovascular disease risk management in primary care settings
por: Rosende, Andres, et al.
Publicado: (2023)

Using FLIM-FRET to Measure Conformational Changes of Transglutaminase Type 2 in Live Cells
por: Caron, Nicholas S., et al.
Publicado: (2012)

Author Correction: Sulfated glycosaminoglycans inhibit transglutaminase 2 by stabilizing its closed conformation
por: Müller, Claudia Damaris, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_unvv1uvl0ej56to7kfqt629dpg