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Current Status of Standardization of Inhalant Allergen Extracts in Korea

Allergy diagnosis and immunotherapy in Korea rely mostly on imported allergen extracts. However, some allergens that are not important in Western countries are not commercially available, and even the same species of allergen source often displays differences in allergenicity due to amino acid seque...

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Autores principales: Jeong, Kyoung Yong, Lee, Jae-Hyun, Kim, Eun-Jin, Lee, Joo-Shil, Cho, Sang-Heon, Hong, Soo-Jong, Park, Jung-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021236/
https://www.ncbi.nlm.nih.gov/pubmed/24843793
http://dx.doi.org/10.4168/aair.2014.6.3.196
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author Jeong, Kyoung Yong
Lee, Jae-Hyun
Kim, Eun-Jin
Lee, Joo-Shil
Cho, Sang-Heon
Hong, Soo-Jong
Park, Jung-Won
author_facet Jeong, Kyoung Yong
Lee, Jae-Hyun
Kim, Eun-Jin
Lee, Joo-Shil
Cho, Sang-Heon
Hong, Soo-Jong
Park, Jung-Won
author_sort Jeong, Kyoung Yong
collection PubMed
description Allergy diagnosis and immunotherapy in Korea rely mostly on imported allergen extracts. However, some allergens that are not important in Western countries are not commercially available, and even the same species of allergen source often displays differences in allergenicity due to amino acid sequence polymorphisms. Therefore, it is essential to prepare allergen extracts that reflect regional characteristics. Allergen standardization has been performed since 2009 with the support of the Korea Center for Disease Control and Prevention. Here, we summarize the current status of allergen standardization, focusing on the house dust mite and cockroach. Pollen allergens that are under investigation are also briefly described.
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spelling pubmed-40212362014-05-19 Current Status of Standardization of Inhalant Allergen Extracts in Korea Jeong, Kyoung Yong Lee, Jae-Hyun Kim, Eun-Jin Lee, Joo-Shil Cho, Sang-Heon Hong, Soo-Jong Park, Jung-Won Allergy Asthma Immunol Res Review Allergy diagnosis and immunotherapy in Korea rely mostly on imported allergen extracts. However, some allergens that are not important in Western countries are not commercially available, and even the same species of allergen source often displays differences in allergenicity due to amino acid sequence polymorphisms. Therefore, it is essential to prepare allergen extracts that reflect regional characteristics. Allergen standardization has been performed since 2009 with the support of the Korea Center for Disease Control and Prevention. Here, we summarize the current status of allergen standardization, focusing on the house dust mite and cockroach. Pollen allergens that are under investigation are also briefly described. The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2014-05 2014-02-21 /pmc/articles/PMC4021236/ /pubmed/24843793 http://dx.doi.org/10.4168/aair.2014.6.3.196 Text en Copyright © 2014 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Jeong, Kyoung Yong
Lee, Jae-Hyun
Kim, Eun-Jin
Lee, Joo-Shil
Cho, Sang-Heon
Hong, Soo-Jong
Park, Jung-Won
Current Status of Standardization of Inhalant Allergen Extracts in Korea
title Current Status of Standardization of Inhalant Allergen Extracts in Korea
title_full Current Status of Standardization of Inhalant Allergen Extracts in Korea
title_fullStr Current Status of Standardization of Inhalant Allergen Extracts in Korea
title_full_unstemmed Current Status of Standardization of Inhalant Allergen Extracts in Korea
title_short Current Status of Standardization of Inhalant Allergen Extracts in Korea
title_sort current status of standardization of inhalant allergen extracts in korea
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021236/
https://www.ncbi.nlm.nih.gov/pubmed/24843793
http://dx.doi.org/10.4168/aair.2014.6.3.196
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