Ecto-domain phosphorylation promotes functional recovery from spinal cord injury

Inhibition of Nogo-66 receptor (NgR) can promote recovery following spinal cord injury. The ecto-domain of NgR can be phosphorylated by protein kinase A (PKA), which blocks activation of the receptor. Here, we found that infusion of PKA plus ATP into the damaged spinal cord can promote recovery of l...

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Detalles Bibliográficos
Autores principales: Suehiro, Kenji, Nakamura, Yuka, Xu, Shuai, Uda, Youichi, Matsumura, Takafumi, Yamaguchi, Yoshiaki, Okamura, Hitoshi, Yamashita, Toshihide, Takei, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021324/
https://www.ncbi.nlm.nih.gov/pubmed/24826969
http://dx.doi.org/10.1038/srep04972

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