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Amyloid-beta neuroprotection mediated by a targeted antioxidant
Amyloid-beta (Aβ)-induced neurotoxicity is a major contributor to the pathologies associated with Alzheimer's disease (AD). The formation of reactive oxygen species (ROS), an early response induced by the peptide and oligomeric derivatives of Aβ, plays a significant role in effecting cellular p...
Autores principales: | Giordano, Courtney R., Terlecky, Laura J., Bollig-Fischer, Aliccia, Walton, Paul A., Terlecky, Stanley R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021325/ https://www.ncbi.nlm.nih.gov/pubmed/24828380 http://dx.doi.org/10.1038/srep04983 |
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