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Targeted mutagenesis using CRISPR/Cas system in medaka
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system-based RNA-guided endonuclease (RGEN) has recently emerged as a simple and efficient tool for targeted genome editing. In this study, we showed successful targeted mutagenesis using RGENs in medaka, Oryz...
Autores principales: | Ansai, Satoshi, Kinoshita, Masato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021358/ https://www.ncbi.nlm.nih.gov/pubmed/24728957 http://dx.doi.org/10.1242/bio.20148177 |
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