Double mutation of cell wall proteins CspB and PBP1a increases secretion of the antibody Fab fragment from Corynebacterium glutamicum

BACKGROUND: Among other advantages, recombinant antibody-binding fragments (Fabs) hold great clinical and commercial potential, owing to their efficient tissue penetration compared to that of full-length IgGs. Although production of recombinant Fab using microbial expression systems has been reporte...

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Detalles Bibliográficos
Autores principales: Matsuda, Yoshihiko, Itaya, Hiroshi, Kitahara, Yuki, Theresia, Natalia Maria, Kutukova, Ekaterina Aleksandrovna, Yomantas, Yurgis Antanas Vladovich, Date, Masayo, Kikuchi, Yoshimi, Wachi, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021378/
https://www.ncbi.nlm.nih.gov/pubmed/24731213
http://dx.doi.org/10.1186/1475-2859-13-56

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