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Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory t cells
BACKGROUND: Autophagy regulates innate and adaptive immune responses to pathogens and tumors. We have reported that autophagosomes derived from tumor cells after proteasome inhibition, DRibbles (Defective ribosomal products in blebs), were excellent sources of antigens for efficient cross priming of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021424/ https://www.ncbi.nlm.nih.gov/pubmed/24735498 http://dx.doi.org/10.1186/1479-5876-12-100 |