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Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory t cells

BACKGROUND: Autophagy regulates innate and adaptive immune responses to pathogens and tumors. We have reported that autophagosomes derived from tumor cells after proteasome inhibition, DRibbles (Defective ribosomal products in blebs), were excellent sources of antigens for efficient cross priming of...

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Detalles Bibliográficos
Autores principales:	Ye, Wei, Xing, Yun, Paustian, Christopher, van de Ven, Rieneke, Moudgil, Tarsem, Hilton, Traci L, Fox, Bernard A, Urba, Walter J, Zhao, Wei, Hu, Hong-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021424/ https://www.ncbi.nlm.nih.gov/pubmed/24735498 http://dx.doi.org/10.1186/1479-5876-12-100

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